Manchester City's hopes of an unprecedented quadruple were in tatters on Sunday after holders Wigan Athletic repeated their FA Cup heroics with a stunning 2-1 victory in their quarter-final at the Etihad Stadium.
Jose Mourinho was far from happy after his Manchester United side failed to beat struggling HullCity at Old Trafford on Wednesday, walking out of one interview and claiming in another that he was treated differently from other managers.
Manchester United's unbeaten start to the Premier League has helped the club build momentum before the derby clash against ManchesterCity, striker Wayne Rooney has said.
Jose Mourinho's reshaped Manchester United destroyed Premier League champions Leicester City 4-1 with a performance that thrilled Old Trafford on Saturday and justified his decision to leave out Wayne Rooney. The shake-up seemed to liberate Paul Pogba who led the way with a polished display, heading his first goal for the club on 42 minutes and starting the clever move that led to Juan Mata firing home United's second after 37 minutes.
Manchester City will look to shake off the defensive vulnerability they showed in losing to promoted Cardiff City last weekend when they host Hull City on Saturday.
Manchester City beat Swansea 3-1 to make it a perfect 10 victories under Pep Guardiola, including six in the Premier League, as they recorded their best start to a top-flight campaign. City's victory was the perfect riposte to the Spaniard's old rival Jose Mourinho, who earlier saw his remodelled Manchester United sparkle without the dropped Wayne Rooney, thumping Premier League champions Leicester City 4-1. On a day of goals, both Manchester sides were outscored by Liverpool, who crushed Hull City 5-1 to take their tally to 24 in the past eight games.
Manchester United consolidated their fourth place, on 22 points, after first-half goals from Chris Smalling and Wayne Rooney and a brilliant, morale-boosting strike from Robin van Persie after the break sealed a 3-0 victory over Hull City.
Chelsea surged to the top of the Premier League with a 3-0 home win over Stoke City thanks to goals from Mohamed Salah, Frank Lampard and Willian at Stamford Bridge on Saturday.
Jose Mourinho hailed Marcus Rashford's late contribution against Hull City on Saturday and hinted that the 18-year-old has a big role to play for Manchester United this season.
Chelsea ripped apart Premier League title rivals Arsenal in a 6-0 mauling at Stamford Bridge on Saturday to ensure Arsene Wenger's 1,000th game turned sour and Liverpool and Manchester City kept up the pressure with big wins.
Manchester City produced a blistering first-half performance to win 4-1 at Sunderland in the League Cup third round on Tuesday, inflicting more misery on Dick Advocaat's struggling side.
Arsenal's dramatic Wembley win against Hull City was the most important victory of Arsene Wenger's 18 years in charge, the five-times FA Cup winning manger said on Saturday.
Arsenal snatched a dramatic 2-1 victory over Burnley to keep their title hopes on track after the referee Jon Moss awarded penalties to both sides and sent off home manager Arsene Wenger in injury time.
Manchester City rediscovered their swagger to beat Chelsea 2-0 and move into the quarter-finals of the FA Cup on Saturday, Manuel Pellegrini winning the battle of tactical wits against Jose Mourinho.
Images from the English Premier League matches played on Saturday.
Swansea City sacked manager Bob Bradley on Tuesday less than three months after the American took charge, with the January transfer window looming and the Premier League's second-bottom club desperate to get out of relegation trouble.
Manchester United's past and future collided as debutant James Wilson scored twice in a 3-1 win over Hull City on Tuesday that marked the end of stalwart Nemanja Vidic's Old Trafford career and set tongues wagging about Ryan Giggs.
Earlier this season Arsenal great Henry, who scored 175 Premier League goals for the club, said Sanchez had been Wenger's "best signing in the last six years".
Sergio Aguero struck twice as Manchester City came from behind to beat Burnley 2-1 at Turf Moor in the Premier League on Saturday.
Didier Drogba struck in stoppage time as Chelsea marked Carlo Ancelotti's first Premier League match in charge with a 2-1 victory over Hull City on Saturday.
Late goals from Nicklas Bendtner and Theo Walcott spared Arsenal's blushes and kept them top of the Premier League in a 2-0 victory over Cardiff City as title rivals Manchester City and Chelsea also won on Wednesday.
A controversial late winner by William Gallas earned Arsenal a 2-1 victory over Hull City in their FA Cup quarter-final on Tuesday and set up a last four showdown with Chelsea at Wembley. The other semi-final will be between Manchester United and Everton.
Upcoming matches in the English Premier League.
The schedule of matches in the English Premier League between Saturday, September 26 and Monday, September 28.
Veteran Drogba showed that he still has a lot of steam in him as he scored in Chelsea's win over Spurs, while Aguero continued to top the goal-scorers' list this season, finding the net for City. Images from the EPL matches played across England on Wednesday.
Arsenal visit Liverpool looking for a first league win at Anfield since 2003. Defeat for Arsene Wenger's side will move seventh-placed Liverpool within a point of them, having played a game more.
Manchester United midfielder Angel Di Maria will miss Tuesday's game against Stoke City and is set for an extended spell on the sidelines after limping out of Saturday's 3-0 win over Hull City.
Manchester City made the most of a case of mistaken identity and kept alive their faint title hopes thanks to a much-needed 3-0 victory over 10-man West Bromwich Albion in the Premier League on Saturday.
Leeds United were crowned champions of the second-tier Championship after third-placed Brentford lost 1-0 at Stoke City in their penultimate game of the season on Saturday.
Manchester United defender Rio Ferdinand has been charged with violent conduct following an incident during Saturday's Premier League game against Hull City, the Football Association (FA) said on its website on Tuesday. The England international was involved in a clash with Hull striker Craig Fagan during the second half of United's 4-0 win.
Manchester United cemented third spot and moved four points clear of neighbours Manchester City.
Adam Lallana and Jordan Henderson scored as Liverpool registered their first Premier League win since August with a 2-1 victory over West Bromwich Albion at Anfield on Saturday.
Arsenal shoved Chelsea off the top of the table but Leicester City's Jamie Vardy, with a dazzling hat-trick, was the man of the moment on Saturday as the struggling Premier League champions blew aside Manchester City 4-2.
Southampton returned to the Premier League after a seven year absence when they beat Coventry City 4-0 on Saturday to clinch second place in the Championship (second division) and take the remaining automatic promotion spot.
Upcoming fixtures in the English Premier League.
Manchester City take on Chelsea and champions Manchester United meet West Ham United in the key fixtures of Saturday's programme in the English Premier League.
A cruel own goal by Damien Duff condemned Newcastle United to relegation from the Premier League after they slipped to a 1-0 defeat at Aston Villa on Sunday.
Jose Mourinho takes Manchester United to Hull City with both teams having won their opening two games on the weekend.
Images from the English Premier League matches played on Monday